Beginners Guide to Synergism, explaining most of the game mechanics, game loop and linking to other guides when needed
Synergism Idle Guides
From Game Vault
Synergism is an Incremental game with the game mechanics that is simple to grasp but can be hard to master and these guides will help you to get better understanding of the game, no matter if you are are a completely new beginner player or looking for some data for optimizing your strategies and min maxing.
Synergism Walktrough Starting at Ascention and following all the way up to Singularity
You can also check out this playlist made by Stan Kosh on Youtube for the full playthrough and some guides for important parts of the gameplay if you prefer video format: https://www.youtube.com/playlist?list=PLpaOv0KSQPmoxzGOOuzk5PXjCBjvOjLDq